Thanks for the welcomes all!
We have been visiting Vegas for many years now - started by staying on the strip but once we discovered Downtown we always return there - specifically the Four Queens. Downtown suits our Vegas needs with great VP and easy walking to Casinos (especially at night). The Fremont noise has never been an issue for us.
During the day we sometimes take the bus to the strip. I always enjoy the Secret Garden, the wildlife at the Flamingo, playing VP at Bellagio & Mandalay Bay - however - we do spend most of our time Downtown.
This coming March trip - I want to visit the Book & Stage at the Cosmo and also definitely eat at Pizza Rock, check out Container Park, and stop by Atomic Liquors.